Shahrekord University of Medical Sciences Journal of Multidisciplinary Care 2783-3852 13 2 2025 06 18 The effect of the family-centered empowerment model on the health literacy and self-efficacy of menopausal women in Iran 67 74 10.34172/jmdc.1287 EN Fatemeh Sadat Hosseini-Baharanchi https://orcid.org/0000-0003-1633-2635 Ziba Raisi Dehkordi https://orcid.org/0000-0003-1861-8143 Shahnaz Kohan https://orcid.org/0000-0003-1479-2160 Hadis Sourinejad https://orcid.org/0000-0003-3508-0971 Elham Adib Moghaddam https://orcid.org/0000-0001-9213-250X Journal Article 10.34172/jmdc.1287 2024 03 18 2024 12 02 Background and aims: This study aimed to assess the effect of the Family-Centered Empowerment Model on the self-efficacy and health literacy of Iranian menopausal women. Methods: This randomized controlled trial (RCT) was carried out on 80 menopausal women aged 40–59 years. The participants were divided randomly into an intervention group (n=40) and a control group (n=40). Results: The results showed that the design and implementation of a Family-Centered Empowerment Model can enhance the health literacy and self-efficacy of menopausal women. Conclusion: Family-Centered Empowerment Model for health literacy and self-efficacy can be crucial in managing menopausal symptoms. Therefore, authorities should consider this model as a strategy for enhancing quality of life and health of menopausal women.